David Plaut spent a number of years developing assays for the clinical laboratory, as well as the first PC-based intra- and inter-laboratory QC system. QC remains an interesting and important area for David, as do method validation, assessing linearity, ROC curves and laboratory statistics in general. He would like to see more data on profiles or panels of some markers for cardiac risk, cancers, DIC, as well as other areas. David has genuine concern about the education of the future generations of clinical laboratory scientists.