Recently in an online issue of the British Medical Journal,
an interventional cardiology specialist registrar at Croydon University Hospital, London, says government obsession with reducing total cholesterol has led to millions of people being overmedicated with statins, when the real issue is not cholesterol but a more complex of 3 lipid abnormalities called "atherogenic dyslipidemia."
The article stated that "recent prospective cohort studies have not supported any significant association between saturated fat intake and cardiovascular risk," and "Instead, saturated fat has been found to be protective,"
On the other hand, a 1994 meta-analysis from the University of Sydney of the effect on coronary events and total mortality in dietary intervention trials found a 6% reduction in mortality and 13% reduction in cardiac events. Most trials prescribed a reduced saturated fat and cholesterol intake with partial replacement by polyunsaturated oils. The review noted that a large controlled trial "may no longer be ethical."
In 2013 a systematic review of cardiovascular disease, information about the role of oxidized LDL and the role of saturated and poly-unsaturated fats role in the formation of atherosclerosis found several studies where polyunsaturated fats are the main contributor to atherosclerosis and coronary heart disease.
Similarly, a 2011 systematic review from The Cochrane Library analyzed 48 studies conducted between 1965 and 2009 and included 65,508 participants. All studies reduced or modified participants' dietary fat or cholesterol by at least 30 percent for at least six months. The conclusion: reducing saturated fat by reducing and/or modifying dietary fat reduced the risk of having a cardiovascular event, such as heart attack, stroke and unplanned heart surgery, by 14 percent. Of the 65,508 participants, 7 percent had a cardiovascular event.
As I write this I am looking at a book titled The Great Cholesterol Myth: Why Lowering Your Cholesterol Won't Prevent Heart Disease.