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April 2014 - Posts

David Plaut: Off the Cuff

Test Utilization
April 29, 2014 11:21 AM by David Plaut
I recently saw big headlines in a Medical Newspaper that a study showed “How Simple Changes in Reporting Medical Laboratory Test Results to Clinicians Improve Patient Safety and Reduce Inappropriate Use of Antibiotics.” As someone who is interested in Read More...
Noteworthy SARS Treatment and Prevention Reviews
April 24, 2014 1:51 PM by David Plaut
Two recent reviews on the prevention and treatment of SARS Severe Acute Respiratory Syndromes and RSV respiratory syncytial virus and influenza virus are worth noting. One of them cautiously rejected some review articles as being biased using the Cochrane Read More...
Kidney Diagnostic Markers
April 22, 2014 4:46 PM by David Plaut
Unlike the progressive development of biomarkers in cardiology, there have been few changes in kidney diagnostic markers. Creatinine is still used as an indicator of kidney function, but not of the parenchymal kidney injury. Serum creatinine concentration Read More...
Sensitivity of Troponin Assays
April 17, 2014 1:50 PM by David Plaut
One of my concerns regarding the increased sensitivity of the available troponin assays (both T and I) is the number of patients with measureable cTn with the newer methods. To a great extent, this concern has been alleviated by a recent study of several Read More...
Use of cTn and BNP in Atrial Fibrillation (AF)-associated Stroke Risk
April 8, 2014 10:17 AM by David Plaut
Cardiac troponin (cTn), due to its superior clinical sensitivity and tissue specificity, has replaced cardiac enzymes, and is the biomarker of choice in making the critical diagnosis of an acute coronary syndrome (ACS). With increases in analytical, cTn Read More...
Going Beyond Lab on a Chip
April 1, 2014 2:30 PM by David Plaut
In my last blog, I touched on some ideas and tools that are being used to build “labs on chips.” The word “nano” (1.10-9) operates significantly in this area. If you were as excited and intrigued with that blog, read on! For now, we are going to discuss Read More...


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