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David Plaut: Off the Cuff

Has Neutrophil Gelatinase-Associated Lipocalin (NGAL) Made ‘The Big Time'?
November 24, 2014 11:17 AM by David Plaut
During the past few years a number of investigations of NGAL have demonstrated that this marker is a "useful biomarker in clinical nephrology which is helpful to diagnosis and evaluate the categories for CKD proposed by the KDIGO." In a recent study Xiang Read More...
Reporting Hemoglobin A1c – SI or per cent?
September 30, 2014 9:59 AM by David Plaut
There was a point-counterpoint “debate” in a recent issue of Clinical Lab News. Arguing for reporting A1c as SI was Ian Young from Ireland; for keeping A1c as percentage -- at least in the United States -- was David Sacks from the NIH in Bethesda, MD. Read More...
Body on a Chip
June 17, 2014 10:55 AM by David Plaut
In a recent blog, I touched on some ideas and tools that are being used to build "labs on chips." The word nano operates significantly in this area. If you were as excited and intrigued with that blog, read on for now we are going to talk on "organs-on-a-chip" Read More...
Lab on a Chip
March 25, 2014 11:54 AM by David Plaut
This is such a fascinating and significant area of our work that I am going to devote both this and the next blog to some recent articles that discuss Lab on a Chip. [There is a journal (Lab Chip) devoted to this. In the last 6 months at PubMed, there Read More...
Managing MRSA
July 15, 2013 4:30 PM by David Plaut
A recent article and editorial in the New England J. Medicine may have answered the question as to how best to deal with the question of MRSA infections in hospital admissions. The study design as published in the New England J. Med [368:2255-226, 2013] Read More...
Myocardial Infarction Protocol
May 23, 2013 11:33 AM by David Plaut
One of my pet concerns is the best rule out myocardial infarction protocol. Best includes rapid, high sensitive and high specificity tests with as few markers as possible. Recently, two articles from Australia and New Zealand added significant data to Read More...
AIDS Update
September 12, 2011 7:37 AM by David Plaut
Recently there was a conference on AIDS in Rome. Two encouraging topics were discussed. The first point is how the use of antiretroviral drugs has not only revolutionized treatment of HIV infection, but also points to stopping the spread of the virus. Read More...
Impact of False Positives
August 22, 2011 7:23 AM by David Plaut
About two years ago, researchers in Nevada published data suggesting the patients with chronic fatigue syndrome may be infected with xenotropic murine leukemia virus. This report created a good bit of anticipation among the one million Americans (not Read More...


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