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ADVANCE Outlook: Lab Professionals

Information Overload

Published January 9, 2013 12:42 PM by Michael Jones

As medical technology becomes more precise and continues to deliver growing quantities of data, the process of analyzing such large figures can be overwhelming. A recent news briefing from DarkDaily reported unstructured medical laboratory data as “one significant hurtle on the path toward the universal electronic health record” (EHR), marking a breakthrough for researchers at MIT in the interpretation of this information.

According to the news briefing, Anna Rumshisky, PhD, Assistant Professor in MIT’s department of computer science, noted the popularity of synoptic pathology reports (SPR) and incorporated an algorithmic approach. The problem with SPR is the open-ended appearance in which the information is structured.  By adopting a technique based on top modeling, an area of research that “seeks to automatically identify the topics of documents by inferring relationships between prominently featured words,” the MIT research team used word-sense disambiguation (WSD) to develop a method of data analytics that could potentially impact EHR and electronic medical records (EMR) as a whole – “more accurate systems that require less human intervention.” 

In the US, WSD and top modeling have proven reliable in the understanding of clinical notes – “an average accuracy rate of 75 percent,” as opposed to the previous 63 percent average. Across the pond, however, researchers have been employing data visualization to interpret big data in fields like molecular biology. A story from LaboratoryNews chronicled the role of specialist biostatisticians and bioinformaticians in data analysis over the expert scientists and researchers who performed the tests originally, stating that a combined effort from both groups is necessary in providing quality results.

“Of course, I still think that a good collaboration between statisticians and biologists is vital,” said Anna Andersson, a scientist studying childhood leukemia. “It is very useful, for example, to discuss cut-offs and statistical significance with a statistician in order to make sure that the data is not ‘over-interpreted.’ However, with the latest data visualization tools, a biologist is now able to query the data instantly, and to be perhaps more critical about the data, by looking at the information in a way that is different from a statistician.”

In an effort to ensure this “partnership,” data is visually being displayed on a screen using powerful software “designed to take full advantage of the most powerful pattern recognizer that exists: the human brain.” This approach has made great strides in areas like genome sequencing, utilizing visualization and mathematical techniques like heatmaps and principal component analysis (PCA) to interpret large amounts of data.

With the flood of information rising from improvements in new technology, the idea of big data simplified into visual structures allows for the promise of testing that can be analyzed as quickly as it was administered. On the other hand, the DarkDaily news release cited unstructured data analysis as “one reason why clinical laboratory managers and pathologists may want to follow further developments with this research.” As interpretive software continues to improve, electronic record keeping is becoming solidified as a standard in the medical industry.  

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