Developments for Platelet Rich Plasma in Aesthetics and Sexual Health
Platelet rich plasma (PRP) has been popularized in sports medicine by injured star athletes. PRP is used to augment the body's natural healing response. Supraphysiologic concentrations of platelet rich plasma are used to facilitate tissue repair, relieve symptoms of pain and improve function by modulating inflammation of injured tendons, ligaments and joints.
Several fields of medicine, including wound care, ophthalmology, dentistry, maxillofacial surgery, urology, dermatology and cosmetic surgery, use this technology to treat various conditions in their specialties.
PRP has been part of our armamentarium for skin rejuvenation for several years. Patients frequently return for the brilliant "glow" they experience for a few days after their treatment. PRP can be delivered alone, injected directly into the skin, combined with hyaluronic acid or applied during microneedling or fractional CO2 laser resurfacing to enhance the rejuvenation.
Platelet derived growth factors are released from the alpha granules in platelets after activation with thrombin, calcium or the tissue's own collagen. The growth factors and cytokines involved include the following:
BFGF-Basic fibroblast growth factor
ECGF-Endothelial cell growth
IGF-Insulin-like growth factor
PD-EGF-Platelet-derived epidermal growth factor
PDGF-Platelet-derived growth factor
TGF-Transforming growth factor
VEGF-Vascular endothelial growth factor
Cell proliferation, cell differentiation (unipotent stem cells) and angiogenesis occur.
Platelet rich plasma involves concentrating the platelets about one-and-a-half times for skin rejuvenation purposes. Various areas where skin rejuvenation is desired and PRP is used include the face, neck, décolleté, arms, legs and breasts. A recent article published in March 2016 in the Daily Mirror demonstrated a "Vampire Breast Lift" to benefit areas of irregularities and asymmetry of the breasts. PRP is used to improve the appearance of post-surgical scars as well as improve sensation. Multiple studies are proving PRP to stimulate nerve regeneration.
The latest exciting area in sexual health is PRP for vaginal rejuvenation called the O-Shot. It is effective in treating urinary incontinence as well as enhancing orgasms.
Patients are attached to platelet rich plasma procedures, because PRP utilizes their own natural regenerative abilities. Autologous PRP injected into tissue contributes to collagenesis, angiogenesis, as well as neurogenesis, resulting in healthier, more youthful tissue with improved sensation.